Therapeutic Impact of α-Mangostin and Hyperbaric Oxygen on Alveolar Bone Cell Activity and MMP-8 Expression

This study investigated the effects of α-mangostin and hyperbaric oxygen therapy on bone remodeling after orthodontic tooth retraction. In animal models, these treatments increased osteoblasts, reduced osteoclast activity, and elevated MMP-8 expression, showing a strong positive correlation among these indicators. The results suggest that both therapies, especially in combination, can enhance alveolar bone repair during orthodontic treatment.

Read full paper : https://doi.org/10.26538/tjnpr/v8i8.32

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