The α-Mangostin and Hyperbaric Oxygen Therapy: Catalysts of Bone Growth Factors Regeneration in Alveolar Bone After Orthodontic Retraction

This animal study evaluated α-mangostin and hyperbaric oxygen therapy after orthodontic retraction. The combination enhanced bone regeneration by increasing VEGF, FGF-2, ALP, and balancing MMP-8, osteoblasts, and osteoclasts. Findings suggest both therapies, especially combined, positively support alveolar bone remodeling.

Read full paper : https://doi.org/10.52711/0974-360X.2025.00100

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