September 2025

Dental caries prevention as a modifiable precipitating factor of nephrotic syndrome relapse in children: an insight into simple-novel management

This retrospective study investigated the association between dental caries and relapse in children with nephrotic syndrome (NS). Among 2,322 recurrent NS cases, 96.4% were linked to dental caries. Children with caries had a significantly higher risk of frequent NS relapse (RR = 42.014, p < 0.001). The findings highlight the need for close collaboration between […]

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In vivo toxicity of chitosan-based nanoparticles: a systematic review

This review summarizes the safety profile of chitosan-based nanoparticles used in drug delivery. Toxicity studies from 2014–2024 show that these nanoparticles generally have low toxicity and are safer than free drugs. Acute toxicity tests reported high LD50 values (>5000 mg/kg), and subacute studies showed no significant adverse effects. Multiple administration routes (oral, intravenous, intraperitoneal, inhalation,

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Age at Primary Surgery among Persons Born with Orofacial Clefts in Africa

This study assessed the age of primary surgery for orofacial clefts (OFCs) in African children using data from 161,035 patients across 40 countries. Only 28.8% received timely surgery (≤6 months for cleft lip, ≤12 months for cleft palate), while over 70% underwent surgery later than recommended. Although surgical volume and early intervention rates improved from

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The Role of Inflammatory Biomarkers (IL-1, IL-6, TNF-α, and Alpha-Amylase) in Saliva on Post-Odontectomy Swelling: A Rapid Review

This review examined the role of salivary inflammatory biomarkers—IL-1, IL-6, TNF-α, and alpha-amylase—in post-odontectomy swelling. Analysis of 10 clinical studies showed that levels of these biomarkers rise after surgery, correlating with increased swelling, pain, and stress. Elevations result from tissue manipulation, immune cell recruitment, and vascular changes. The study highlights the potential of these biomarkers

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Research for Partnership for The Goals

SDG 17 – Partnerships for the Goals💰 Total research funding: Rp90,000,000 These studies aim to strengthen global health collaborations 🌍🤝 through birth defect surveillance systems in low- and middle-income countries 🏥📊 and the Pentahelix model for caries management toward a Caries-Free Indonesia 2030 🦷🇮🇩. By building multi-sector partnerships, this research contributes to sustainable development and

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Research for Peace, Justice, and Strong Institution

SDG 16 – Peace, Justice, and Strong Institutions💰 Total research funding: Rp213,615,000 These studies focus on 3D radioidentification, DNA analysis of dental pulp, and craniofacial morphometrics 🦷🧬, enabling age estimation, individual identification, and detection of oromaxillofacial variations 📸🦴. The research supports forensic science, justice, and accurate human identification, contributing to stronger institutions and fair legal

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Research for Life on Land

SDG 15 – Life on Land💰 Total research funding: Rp288,500,000 These studies explore the antibacterial and bioactive potential of natural extracts 🌿🦷, including Moringa oleifera leaf nanohydrogel, Terpenoid A from ant nest (Myrmecodia pendens), and Kaempferia galanga & Lemongrass 🍃. The research targets periodontal pathogens, biofilm control, anti-inflammatory and antioxidant activities, promoting oral health through

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Research for Life Below Water

SDG 14 – Life Below Water💰 Total research funding: Rp46,500,000 This research develops a multifunctional barrier membrane made from carp fish scale collagen 🐟🦷, exhibiting antibacterial and osteogenic activities for the treatment of periodontal bone defects 🦴✨. It exemplifies the sustainable use of aquatic resources in biomedical applications 🌱🔬. #SDG14#LifeBelowWater#MarineConservation#SustainableMaterials#DentalResearch#fkgunpad

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Research for Climate Action

SDG 13 – Climate Action💰 Total research funding: Rp273,790,000 This research focuses on the development of biocompatible and sustainable scaffolds using Chitosan-Graphene Oxide and Vaterite CaCO₃ for bone tissue engineering 🦴🔬. Such innovations support environmentally conscious biomedical materials and sustainable health solutions 🌱✨. #SDG13#ClimateAction#GreenDentistry#SustainableResearch#DentalInnovation#fkgunpad

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Research for Responsible Consumption and Production

SDG 12 – Responsible Consumption and Production💰 Total research funding: Rp1,158,180,000 This research focuses on sustainable and natural approaches in oral health 🌱🦷. Topics include the effects of switching from tobacco to alternative products on gingiva 🚭, the use of potato peel and aloe vera extracts for wound healing and remineralization 🥔🌿, and the development

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