Fakultas

This study investigated gingerols and shogaols from Zingiber officinale var. sunti as potential anti-anxiety agents targeting the human GABAA receptor. Molecular docking and dynamics showed 6-gingerol and 10-shogaol had stable binding comparable to diazepam, supported by phytochemical analysis of the extract. These compounds may act as natural allosteric agonists of GABAA receptors, though with lower […]

This case report of four patients with tongue squamous cell carcinoma (TSCC) shows that radiotherapy often causes painful oral side effects like candidiasis, mucositis, and xerostomia, which can hinder treatment adherence. Supportive care using antifungals, hyaluronic acid mouthwash, diphenhydramine, and artificial saliva improved oral health-related quality of life (OHRQoL) and reduced pain levels, highlighting the

This study compared facial proportions of stunted and non-stunted children in Bandung, Indonesia. Results showed that stunted children had significantly shorter vertical facial dimensions, while horizontal dimensions were similar across groups. These findings suggest that vertical facial measurements could serve as supportive, non-invasive indicators for early detection and monitoring of childhood stunting in community settings.

This study of 343 Indonesian schoolchildren found that mouth breathers had a significantly higher risk of sleep-disordered breathing (SDB). About 41% of mouth-breathing children showed SDB symptoms compared to 9.7% of non-mouth breathers, with a 4.24 times greater risk. Early screening and intervention are recommended to prevent related health issues. Read full paper : https://www.scopus.com/pages/publications/105014826763

This study reviewed 36 RCTs on non-combustible nicotine products and found that oral adverse event (OAE) reporting was incomplete and inconsistent. Most trials lacked clear definitions, severity measures, and standardized reporting methods. Although some provided quantitative data, overall reporting quality has not significantly improved over time. The authors stress the need for standardized OAE reporting

This study evaluated the antimicrobial and antioxidant properties of Nigella sativa (black cumin) seed ethanol extract (BCSE) for oral health applications. BCSE showed concentration-dependent antibacterial activity against Porphyromonas gingivalis, Streptococcus mutans, and Candida albicans, as well as strong antioxidant activity in multiple assays. The findings suggest that BCSE could serve as a natural, plant-based ingredient

This systematic review evaluated anodized titanium dental implant abutments, which modify titanium’s surface color to improve esthetics. Across nine RCTs, anodized abutments—especially pink tones—enhanced soft tissue aesthetics and color harmony, particularly in patients with thin gingiva. However, clinical improvements in inflammation, plaque, or mucosal recession were minimal and inconsistent. While anodization is safe and visually

This systematic review evaluated Digital Smile Design (DSD) in dentistry, focusing on aesthetics, patient satisfaction, and sustainability. Across 12 studies, DSD improved smile aesthetics, including alignment, tooth shape, and lip symmetry, while increasing patient satisfaction due to precision, reduced chair time, and minimally invasive procedures. Additionally, DSD offers eco-friendly benefits by minimizing material waste and

This retrospective study investigated the association between dental caries and relapse in children with nephrotic syndrome (NS). Among 2,322 recurrent NS cases, 96.4% were linked to dental caries. Children with caries had a significantly higher risk of frequent NS relapse (RR = 42.014, p < 0.001). The findings highlight the need for close collaboration between

This review summarizes the safety profile of chitosan-based nanoparticles used in drug delivery. Toxicity studies from 2014–2024 show that these nanoparticles generally have low toxicity and are safer than free drugs. Acute toxicity tests reported high LD50 values (>5000 mg/kg), and subacute studies showed no significant adverse effects. Multiple administration routes (oral, intravenous, intraperitoneal, inhalation,